Cyflumetofen [iso]
2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate
CAS: 400882-07-7
Molecular Formula: C24H24F3NO4
Cyflumetofen [iso] - Names and Identifiers
Cyflumetofen [iso] - Physico-chemical Properties
| Molecular Formula | C24H24F3NO4 |
| Molar Mass | 447.45 |
| Density | 1.214 |
| Boling Point | 533.8±50.0 °C(Predicted) |
| Flash Point | 276.611°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | neat |
| BRN | 11332768 |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.511 |
Cyflumetofen [iso] - Risk and Safety
| Risk Codes | R20 - Harmful by inhalation R43 - May cause sensitization by skin contact R50 - Very Toxic to aquatic organisms |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 2 |
Cyflumetofen [iso] - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| overview | bufenflurinate (cyflumetofen) is a benzoyl acetonitrile acaricide developed by Otsuka Chemical Company of Japan. it was registered and sold in Japan in 2007 and is mainly used for the control of mites such as fruit trees, vegetables and ornamental plants. This variety has no cross resistance with existing insecticides, has no adverse effects on non-target organisms, beneficial organisms, etc., and can quickly decompose and metabolize in water and soil, which is conducive to environmental protection. It is today's acaricide One of the best choices. Buflumite is a new type of acaricide of benzoyl acetonitrile. It has no cross-resistance with existing insecticides. Buflumite has a low hatching effect on preventing red spider eggs, but it has high activity at all growth stages. However, due to the easier hydrolysis of buflumite, it has a short duration, which leads to a great impact on its control effect. Therefore, in order to ensure the control effect, it not only causes environmental pollution, but also affects the whole market prospect of buflumite. Therefore, the development of a polymer or natural material to encapsulate buflumilate, so that its active ingredients in a certain dose of release, not only to play the acaricidal effect, but also to extend the duration, effectively reduce the use of drugs while also protecting the environment. In addition, there are few reports on the synthesis process of buflumite in China, and there are not many manufacturers. The products supplied by commodities have high prices, many impurities, and the content is only about 85%, which is very easy to produce key points. Therefore, the research can obtain the production process with low cost and high content, which has important practical and economic significance. |
| use | buflumite (20% SC) is mainly used to control harmful mites on fruit trees, cotton, vegetables, tea and other crops. The table is the insecticidal and acaricidal spectrum of buflumite. The agent has high activity against spider mite and whole claw mite, but is almost inactive against lepidoptera, homoptera and tassoptera pests. The agent has good activity on mites at all stages of development, and its control effect on juvenile mites is much higher than that of adult mites. The agent has no cross-resistance with other acaricides, and has a significant control effect on mites that have developed resistance. The field test results showed that the 20% of buflumite was effective against spider mite in the dose range of 100-800g/hm2. No toxicity was found under routine dosage. |
| mechanism of action | buflumilate is a non-systemic acaricide, and the main mode of action is contact killing. After entering the insect body through contact, it can be metabolized in the mite body to produce a highly active substance AB-1. The results showed that AB-1 had a strong inhibitory effect on the mitochondrial complex of Tetranychus mites, and its IC50 was 6.55 nm. With the continuous metabolism of bufenflurate in mites to AB-1, the concentration of AB-1 continues to rise, the respiration of mites is more and more inhibited. Finally, the prevention and control effect is achieved. It is inferred that the main mechanism of action of buflumite is to inhibit the respiration of mites mitochondria. |
Last Update：2024-04-10 22:29:15
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